Selected Publications
Fingerman DF, O'Leary DR, Hansen AR, Tran T, Harris BR, Hayer KE, Tennekoon M, DeWeerd RA, Meroni A, Szeto JH, Weitzman MD, Shalem O, Bednarski J, Vindigni A, Green AM (2024). The SMC5/6 complex is required for maintenance of genome integrity upon APOBEC3A-mediated replication stress. The EMBO Journal. PMID 38886582. PDF
Petljak, M., Green, A. M., Maciejowsk, J., Weitzman, M. D. (2022). Addressing the therapeutic potential of inhibiting APOBEC3-mutagenesis in cancer. Nature Genetics, 54(11): 1599-1608. PDF
DeWeerd, R. A., & Green, A. M. (2022). Qualitative and quantitative analysis of DNA-cytidine deaminase activity. Methods Mol Biol, 244: 161-169. PDF
DeWeerd, R. A., Németh, E., Póti, Á., Petryk, N., Chen, C. L., Hyrien, O., Szüts, D., Green, A. M. (2022). Prospectively defined patterns of APOBEC3A mutagenesis are prevalent in human cancers. Cell Reports, 38, 110555. PDF
Berrios, K. N., Evitt, N H., DeWeerd, R. A., Ren, D., Barka, A., Wang, T., Bartman, C. R., Lan, Y., Green, A. M., Shi, L., Kohli, R. M. (2021). Controllable genome editing with split-engineered base editors. Nat Chem Bio, 17(12): 1262-1270. PDF
Green, A. M., DeWeerd, R. A., O’Leary, D. R., Hansen, A. R., Hayer, K. E., Kulej, K., Dineen, A. S., Szeto, J. H., Garcia, B. A., Weitzman, M. D. (2021). Interaction with the CCT chaperonin complex limits APOBEC3A cytidine deaminase cytotoxicity. EMBO Reports, 22: e52145. PDF
Green, A. M., & Weitzman, M. D. (2019). The spectrum of APOBEC3 activity: From anti-viral agents to anti-cancer opportunities. DNA repair, 83, 102700. PDF
Green, A. M., Budagyan, K., Hayer, K. E., Reed, M. A., Savani, M. R., Wertheim, G. B., & Weitzman, M. D. (2017). Cytosine Deaminase APOBEC3A Sensitizes Leukemia Cells to Inhibition of the DNA Replication Checkpoint. Cancer research, 77(17), 4579–4588. PDF
Green, A. M., Landry, S., Budagyan, K., Avgousti, D. C., Shalhout, S., Bhagwat, A. S., & Weitzman, M. D. (2016). APOBEC3A damages the cellular genome during DNA replication. Cell cycle (Georgetown, Tex.), 15(7), 998–1008. PDF
Additional publications from the Green lab can be found here